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目的:研究肝纤维化患者检测指标的临床意义。方法:检测凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、血浆凝血酶时间(TT)、血浆纤维蛋白原(FIB)、D-二聚体(D-D)及纤维蛋白原降解产物(P-FDP)的值。结果:PT值、APTT、TT、FIB值均随着疾病严重程度而增加,且与正常组比较,差异有统计学意义(P<0.05)。FDP在不同的含量中的阳性率,随着疾病严重程度加剧,则高浓度中的FDP例数增加。结论:肝纤维化患者检测PT值、APTT、TT、FIB和FDP值的变化,可从多方面客观准确地评价肝纤维化患者的病情及凝血功能状况,值得临床推广。
Objective: To study the clinical significance of detection indexes in patients with liver fibrosis. Methods: Prothrombin time, active partial thromboplastin time, TT, FIB, DD and fibrinogen Product (P-FDP) value. Results: The PT, APTT, TT and FIB values increased with the severity of the disease, and the difference was statistically significant (P <0.05). The positive rate of FDP at different levels increased with the severity of the disease as the number of FDP cases at high concentrations increased. Conclusion: The changes of PT, APTT, TT, FIB and FDP in patients with liver fibrosis can objectively and accurately evaluate the condition and coagulation status of patients with liver fibrosis in many aspects, which is worthy of clinical promotion.