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目的探讨糖尿病血脂、血尿酸(HOA)与高血压的关系。方法测定34例,糖尿病合并高血压,胰岛素敏感性脂数(LS1)、胰岛素抵抗指数(HOMA、LR)及胰岛β细胞分泌功能脂数(HOMA-b)并与非糖尿病高血压(NDACI)患者对照组(NC)比较。结果 HOA组FPCT、FINS、HOMA、TR及血脂、血尿酸(SOA)水平明显高于NC组、ISI明显低于NC组,差异均有统计学意义(P均<0.01)排除年龄及入选病例时已除外的,高血压等相关因素,HVA与IR密切相关。结论糖尿病合并高血压(DACI)血脂、血尿酸关系是代谢综合征的危险因素之一。
Objective To investigate the relationship between diabetes mellitus, serum uric acid (HOA) and hypertension. Methods 34 patients with diabetes mellitus, hypertension, insulin sensitivity index (LS1), insulin resistance index (HOMA, LR) and pancreatic β-cell secretory function number (HOMA-b) were measured in patients with non-diabetic hypertension Control group (NC) comparison. Results The levels of FPCT, FINS, HOMA, TR, serum lipids and serum uric acid in HOA group were significantly higher than those in NC group and ISI was significantly lower than those in NC group (all P <0.01) Excluded, high blood pressure and other related factors, HVA and IR are closely related. Conclusion The relationship between blood lipid and serum uric acid in diabetes mellitus with hypertension (DACI) is one of the risk factors of metabolic syndrome.