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输注白蛋白可以改善合并自发性细菌性腹膜炎(SBP)肝硬化患者的肾功能和生存率,但对其他类型感染的肝硬化患者效果尚不明确。来自法国的Thévenot T等通过多中心随机对照试验对这一问题进行探究。研究共纳入193例Child-Pugh评分>8分,合并感染(除外SBP)的肝硬化患者,随机分为白蛋白组96例(接受抗生素+白蛋白,白蛋白1.5 g·kg-1·d-1,1 g·kg-1·3d-1)和对
Albumin infusion improves renal function and survival in cirrhotic patients with spontaneous bacterial peritonitis (SBP), but the effect is not clear for other types of cirrhosis. Thévenot T et al from France explored this issue through a multicenter randomized controlled trial. A total of 193 patients with cirrhosis who had a Child-Pugh score> 8 and who had a combined infection (except for SBP) were enrolled in this study. They were randomly divided into 96 albumin groups (antibiotics + albumin, albumin 1.5 g · kg -1 · d- 1,1 g · kg -1 · 3d-1) and the pair