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观察静脉注射东氯合剂(每m l含东莨菪碱0.3m g,氯丙嗪12.5m g)对麻醉家犬的血压、呼吸和心率的影响。结果表明:东氯合剂剂量分别在0.033、0.1、0.3、0.9m l/kg 时,家犬血压有不同程度下降,呈现剂量依赖性,但均在1~3m in 后恢复到正常水平,降压幅度略低于等量的氯丙嗪,单用东莨菪碱血压和心率有轻度上升;仅在降压的同时呼吸有反射性加速现象。提示东莨菪碱与氯丙嗪合用对血压有轻度保护作用。
To observe the effects of intravenous injection of East-chlorine mixture (0.3 m g per 1 cm of scopolamine and 2.5 mg of chlorpromazine) on blood pressure, respiration and heart rate in anesthetized dogs. The results showed that the blood pressure of dogs decreased in a dose-dependent manner at doses of 0.033, 0.1, 0.3 and 0.9m l / kg, respectively, in a dose-dependent manner. However, Returned to normal levels, blood pressure slightly lower than the equivalent of chlorpromazine, single use of scopolamine blood pressure and heart rate increased slightly; only in the antihypertensive respiratory reflex phenomenon. Prompt scopolamine and chlorpromazine in combination with mild protection of blood pressure.