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现今艮他霉素广泛应用于治疗化脓性眼科疾病。艮他霉素在治疗严重的眼内感染如眼内炎等疾病方面疗效尤为突出,但是抗生素必须直接滴入眼内,因此必须研究眼组织对艮他霉素的耐受性,选择允许的浓度和剂量。然而目前有关的资料很少,而且结论也不一致,所以作者选择家兔进行了耐受性的试验。试验结果表明,滴入结膜囊2%和8%的艮他霉素引起了角膜上皮的中等水肿;滴入1%和0.5%的药液,眼睛没有出现任何病理变化。
Today, gentamicin is widely used in the treatment of purulent ophthalmic diseases. The efficacy of gentamicin in the treatment of severe intraocular infections such as endophthalmitis is particularly prominent, but antibiotics must be directly dripped into the eye, it is necessary to study the eye tissue tolerance to gentamicin, select the allowable concentration And dose. However, little information is available at present, and the conclusions are inconsistent. Therefore, the author chose to test the tolerance of rabbits. The test results showed that 2% and 8% of gentamicin dripped into the conjunctival sac caused a moderate edema of the corneal epithelium; 1% and 0.5% of the medicinal solution was dropped into the eye without any pathological changes.