论文部分内容阅读
目的:观察和分析左氧氟沙星治疗耐多药肺结核的临床效果及安全性。方法:选取我院2013年5月~2014年5月收治的92例耐多药肺结核患者,通过抛硬币随机分组法分为对照组(n=46)及观察组(n=46),两组患者均给予常规治疗,对照组患者采用氧氟沙星治疗,观察组患者采用左氧氟沙星治疗,对两组患者临床治疗效果、不良反应发生情况进行分析。结果:观察组患者治疗总有效率93.48%,高于对照组治疗有效率82.61%(P<0.05);观察组患者不良反应发生率4.35%,低于对照组21.74%,差异具有统计学意义(P<0.05)。结论:采用左氧氟沙星治疗耐多药肺结核患者疗效确切,有利于缓解临床症状,减轻患者身心痛苦,不良反应少,安全系数高,疗效安全显著,具有重要的临床应用价值。
Objective: To observe and analyze the clinical efficacy and safety of levofloxacin in the treatment of multi-drug resistant pulmonary tuberculosis. Methods: A total of 92 MDR-TB patients admitted to our hospital from May 2013 to May 2014 were selected and randomly divided into control group (n = 46) and observation group (n = 46) Patients were given conventional treatment, the control group of patients treated with ofloxacin, the observation group of patients treated with levofloxacin, the two groups of patients with clinical treatment, adverse reactions were analyzed. Results: The total effective rate was 93.48% in the observation group, 82.61% higher than that in the control group (P <0.05). The incidence of adverse reactions in the observation group was 4.35%, lower than that in the control group (21.74%), the difference was statistically significant P <0.05). Conclusion: The levofloxacin treatment of multidrug-resistant pulmonary tuberculosis is effective in relieving clinical symptoms, alleviating the physical and psychological pain, fewer adverse reactions, high safety factor and significant curative effect. It is of great clinical value.