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目的探讨乙肝后肝硬化患者采用跟踪护理对抗病毒药物治疗依从性的影响。方法回顾性分析125例抗病毒药物治疗的乙肝后肝硬化患者临床资料,按照不同护理方法分为对照组(55例)和研究组(70例),对照组采用常规护理,研究组采用跟踪护理,对比2组治疗依从性、护理满意度及抗病毒药物治疗情况。结果研究组治疗依从性88.57%高于对照组69.09%(P<0.05);研究组健康知识宣教、出院指导、出院回访及服务态度依次为(23.17±5.59)分、(22.65±5.88)分、(21.56±5.74)分及(24.39±5.41)分均显著优于对照组(13.23±5.26)分、(12.24±3.85)分、(11.66±4.22)分及(13.23±3.98)分(P<0.05);研究组HBe Ag转阴率47.14%、HBV-DNA转阴率82.86%高于对照组20.00%、56.36%,且病毒变异5.71%低于对照组21.82%,差异有统计学意义(P<0.05)。结论乙肝后肝硬化患者采用跟踪护理可增强治疗依从性,从而可以提高患者满意度同时,能够增强抗病毒药物治疗效果。
Objective To investigate the effect of follow-up care on compliance of anti-viral drugs in patients with posthepatitic cirrhosis. Methods The clinical data of 125 patients with posthepatitic cirrhosis treated with antiviral drugs were retrospectively analyzed. The patients were divided into control group (55 cases) and study group (70 cases) according to different nursing methods. The control group received routine nursing. The study group was treated with follow-up care , Compared with two groups of treatment compliance, nursing satisfaction and antiviral drug treatment. Results The compliance rate of the study group was 88.57% higher than that of the control group (69.09%) (P <0.05). In the study group, the attitude toward health education, discharge guidance, discharge return and attitude were 23.17 ± 5.59 and 22.65 ± 5.88, (21.56 ± 5.74) and (24.39 ± 5.41) points were significantly better than the control group (13.23 ± 5.26), (12.24 ± 3.85) points, (11.66 ± 4.22) points and (13.23 ± 3.98) points ). The negative rate of HBe Ag in research group was 47.14%, the negative rate of HBV-DNA in DNA was 82.86% higher than that of control group (20.00%, 56.36%), and the variation of virus was 5.71% lower than that of control group (21.82%, P < 0.05). Conclusion Follow-up care in patients with posthepatitic cirrhosis can enhance treatment compliance, which can improve patient satisfaction and enhance the therapeutic effect of antiviral drugs.