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131I治疗儿童和青少年Graves病(GD)的成功率可达90%,甲状腺功能亢进(甲亢)患者接受131I治疗后,甲状腺癌形成、性腺损伤及后代获得先天性畸形的风险没有明显的增加。年幼的GD儿童用131I治疗,甲状腺癌的风险可能有较小程度的增加。131I治疗对儿童甲状腺眼病的影响不大,也是安全的。131I治疗的优点是安全、简单、经济、有效。对于抗甲状腺药物治疗无效或复发、不愿手术或手术后复发的儿童及青少年甲亢病人,131I治疗是可供选择的一种较好的治疗方法,其可作为儿童及青少年甲亢的第二线治疗。
The success rate of 131I in treating Graves’ disease (GD) in children and adolescents is as high as 90%. There is no obvious increase in thyroid cancer, gonadal injury and the risk of congenital malformations in the offspring after 131I treatment in patients with hyperthyroidism (hyperthyroidism). 131I treatment of young GD children, the risk of thyroid cancer may be increased to a lesser extent. 131I treatment of children with thyroid eye disease little effect, but also safe. The advantages of 131I treatment are safe, simple, economical and effective. 131I treatment is a good alternative treatment for children and young patients with hyperthyroidism who are ineffective or relapse of antithyroid drug therapy, reluctance or recurrence, and can be used as the second line of treatment for hyperthyroidism in children and adolescents.