论文部分内容阅读
1 新生儿缺氧缺血性脑病(HIE)的治疗基础1.1 预防和治疗的重要性严重的缺氧缺血脑损害可产生永久性神经系统缺陷,如脑瘫、智力低下、学习障碍及癫痫。国内外资料都表明约有2～6/100个足月活产儿发生新生儿窒息,其中10%～60%(重症窒息可达80%)发展为 HIE,25%或更多的存活患儿出现神经系统后遗症。较高的发生率使新生儿科医师努力去寻求预防和减少 HIE 的脑损伤和降低后遗症的治疗新方法。但目前治疗本病尚无特殊有效的措施,更应强调预防的重要性。产科和儿
1 Therapeutic Basis for Neonatal Hypoxic Ischemic Encephalopathy (HIE) 1.1 The Importance of Prevention and Treatment Severe hypoxic-ischemic brain damage can produce permanent neurological deficits such as cerebral palsy, mental retardation, learning disabilities and epilepsy. Both domestic and international data indicate that neonatal asphyxia occurs in about 2 to 6 out of 100 live births, of which 10% to 60% (severe asphyxia up to 80%) develop into HIE and 25% or more of surviving infants develop Nervous system sequelae. The high incidence of neonatal pediatricians seek to find new ways to prevent and reduce brain damage and reduce sequelae of HIE. However, there are no special and effective measures for the treatment of this disease at present, and the importance of prevention should be emphasized. Obstetric and pediatric