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目的:观察尿激酶、组织纤溶原激活物配合活血祛瘀汤治疗脑梗死临床疗效。方法 :100例患者随机分为2组,对照组以尿激酶、组织纤溶原激活物治疗,观察组在对照组基础上加用活血祛瘀汤治疗。治疗15天。观察2组患者临床疗效,并记录治疗后血液黏稠度变化情况。结果:总有效率观察组92.00%,对照组78.00%,2组比较,差异有统计学意义(P<0.05)。观察组全血黏度、血浆黏度、血小板聚集率均较对照组低,2组比较,差异均有统计学意义(P<0.05)。观察组治疗24 h、48 h、15天神经功能缺损评分(NIHSS)评分均较对照组低,2组比较,差异均有统计学意义(P<0.05)。结论:尿激酶、组织纤溶原激活物配合自拟活血祛瘀汤治疗脑梗死,临床疗效显著,可提高患者生活质量。
Objective: To observe the clinical effect of urokinase, tissue fibrinogen activator and Huoxue Quyu Decoction in treating cerebral infarction. Methods: One hundred patients were randomly divided into two groups. The control group was treated with urokinase and tissue fibrinogen activator. The observation group was treated with Huoxue Quyu Decoction on the basis of the control group. Treatment for 15 days. The clinical efficacy of the two groups was observed, and the changes of blood viscosity after treatment were recorded. Results: The total effective rate was 92.00% in observation group and 78.00% in control group, the difference was statistically significant (P <0.05). The whole blood viscosity, plasma viscosity and platelet aggregation rate in the observation group were lower than those in the control group. The differences between the two groups were statistically significant (P <0.05). The scores of NIHSS in the observation group at 24 h, 48 h and 15 days were lower than those in the control group. The differences between the two groups were statistically significant (P <0.05). Conclusion: The combination of urokinase and tissue fibrinogen activator in the treatment of cerebral infarction with self-made Huoxue Quyu Decoction can improve the quality of life of patients.