Rare combination of familial adenomatous polyposis and gallbladder polyps

• 作 者: Yasuhisa Mori Norihiro Sato Nobutaka Matayoshi Toshihisa Tamura Noritaka Minagawa Kazunori Shibao Aiichiro Higure Mitsuhiro Nakamoto Masashi Taguchi Koji Yamaguchi
• 机 构: Department of Surgery,School of Medicine,University of Occupational and Environmental Health,Kitakyu
• 出 处: World Journal of Gastroenterology
• 发表日期: 2014年46期
• 关键词: adenomatous gallbladder polyposis familial adenoma colon ascending preoperative

Familial adenomatous polyposis is associated with a high incidence of malignancies in the upper gastrointestinal tract(particularly ampullary adenocarcinomas).However,few reports have described a correlation between familial adenomatous polyposis and gallbladder neoplasms.We present a case of a 60-year-old woman with familial adenomatous polyposis who presented with an elevated mass in the neck of the gallbladder(measuring 16 mm×8 mm in diameter)and multiple small cholecystic polyps.She had undergone a total colectomy for ascending colon cancer associated with familial adenomatous polyposis 22 years previously.The patient underwent laparoscopic cholecystectomyunder a preoperative diagnosis of multifocal gallbladder polyps.Pathologic examination of the resected gallbladder revealed more than 70 adenomatous lesions,a feature consistent with adenoma of the gallbladder.This case suggests a requirement for long-term surveillance of the biliary system in addition to the gastrointestinal tract in patients with familial adenomatous polyposis.

Familial adenomatous polyposis is associated with a high incidence of malignancies in the upper gastrointestinal tract (particularly ampullary adenocarcinomas). Despite, few reports have described a correlation between familial adenomatous polyposis and gallbladder neoplasms. We present a case of a 60-year-old woman with familial adenomatous polyposis who presented with an elevated mass in the neck of the gallbladder (measuring 16 mm × 8 mm in diameter) and multiple small cholecystic polyps. She had undergone a total colectomy for ascending colon cancer associated with familial adenomatous polyposis 22 years previously The patient underwent laparoscopic cholecystectomyunder a preoperative diagnosis of the multifocal gallbladder polyps. Pathologic examination of the resected gallbladder revealed more than 70 adenomatous lesions, a feature consistent with adenoma of the gallbladder. This case suggests a requirement for long-term surveillance of the biliary system in addition to the gastrointestinal tra ct in patients with familial adenomatous polyposis.