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目的探讨血糖对脑梗死患者颈动脉内膜中层厚度的影响。方法对172例急性缺血性卒中患者的颈动脉分叉处内膜中层厚度(IMT)和糖尿病史、空腹血糖及糖化血红蛋白(HbA1c)进行相关性分析,同时分析糖尿病患者的血糖水平和颈动脉IMT的相关性。结果颈动脉IMT增厚组的年龄(P<0.01)、糖尿病比例(P<0.01)、入院时的空腹血糖(P=0.035)及HbAlc(P=0.051)明显增高,其中,年龄(P=0.023)及糖尿病史(P<0.01)和颈动脉IMT的增厚存在独立相关性。在糖尿病患者中,空腹血糖及HbA1c的增高和颈动脉IMT的增厚无显著相关性(P>0.05)。结论急性缺血性卒中患者中,年龄及糖尿病史为颈动脉IMT增厚的独立危险因素。
Objective To investigate the effect of blood glucose on carotid intima-media thickness in patients with cerebral infarction. Methods The carotid bifurcation intima-media thickness (IMT), history of diabetes mellitus, fasting blood glucose and glycosylated hemoglobin (HbA1c) were analyzed in 172 patients with acute ischemic stroke. The levels of blood glucose and carotid artery IMT relevance. Results The IMT thickened group had significantly higher age (P <0.01), diabetes mellitus (P <0.01), fasting blood glucose (P = 0.035) and HbA1c (P = ) And diabetes mellitus (P <0.01) and carotid IMT thickened independent correlation. In patients with diabetes, fasting blood glucose and HbA1c increased carotid IMT thickening and no significant correlation (P> 0.05). Conclusions Among the patients with acute ischemic stroke, the age and the history of diabetes mellitus were independent risk factors of carotid IMT thickened.