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目的:探讨益气养阴补肾泄浊法治疗早期糖尿病肾病(DN)的临床效果。方法:将128例DN患者随机分为对照组和观察组各64例,对照组给予常规治疗,治疗组在对照组治疗的基础上加服益气养阴补肾泄浊中药汤剂,疗程均为2个月,疗程结束后对治疗前、后尿微量白蛋白(mALB)、24h尿蛋白定量(Upro)、血肌酐(SCr)以及尿素氮(BuN)等检测指标进行统计比较。结果:与治疗前比较,两组的尿mALB及24h尿蛋白定量(Upro)、SCr以及BUN等均有所下降,但治疗组的效果要优于对照组,其中尿mALB及24h尿蛋白定量的差异有统计学意义(P<0.05)。结论:合用益气养阴补肾泄浊法治疗DN的疗效明显优于单纯常规治疗。
Objective: To investigate the clinical effects of Yiqi Yangyin Bushen Xiezhuo method in the treatment of early diabetic nephropathy (DN). Methods: A total of 128 patients with DN were randomly divided into control group and observation group, 64 cases in each group. The control group was given routine treatment. The treatment group was given Yiqi Yangyin Bushen Xiezhuo decoction on the basis of the control group. The course of treatment was After 2 months of treatment, the levels of mALB, Upro, SCr and BuN before and after treatment were compared statistically. Results: The urinary mALB and urinary proteinuria (Upro), SCr and BUN decreased in both groups before treatment, but the effect of treatment group was better than that of the control group. The urinary mALB and 24-hour urinary protein The difference was statistically significant (P <0.05). Conclusion: The combined effect of nourishing yin, nourishing yin and invigorating the kidney and voiding turbid method is superior to conventional therapy in treating DN.