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本文报道了以双光气(氯甲酸三氯甲酯)为起始原料合成苯黄隆的方法。该工艺总收率为6541%,苯黄隆原药纯度达到9528%。
In this paper, a method for the synthesis of phenylmeronitrile from phosgene (trichloromethyl chloroformate) is reported. The total yield of the process was 6541%, and the purity of the original drug was 9528%.