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目的分析对比新辅助化疗、单纯放疗与同步放化疗治疗宫颈癌的近期疗效。方法 117例宫颈癌患者,随机分为新辅助化疗组、单纯放疗组及同步放化疗组,各39例。分别给予新辅助化疗、单纯放疗及同步放化疗。观察三组临床疗效与治疗毒副反应。结果同步放化疗组治疗总有效率高于新辅助化疗组与单纯放疗组(P<0.05)。三组治疗毒副反应的发生率对比差异无统计学意义(P>0.05)。结论同步放化疗治疗宫颈癌的近期疗效显著优于新辅助化疗与单纯放疗,适于临床应用。
Objective To analyze and compare the short-term curative effect of neoadjuvant chemotherapy, radiotherapy and concurrent chemoradiotherapy for cervical cancer. Methods 117 patients with cervical cancer were randomly divided into neoadjuvant chemotherapy group, radiotherapy alone group and concurrent radiotherapy and chemotherapy group, 39 cases each. Were given neoadjuvant chemotherapy, radiotherapy alone and concurrent chemoradiation. To observe the clinical efficacy and treatment of three groups of side effects. Results The total effective rate of concurrent radiochemotherapy group was higher than that of neoadjuvant chemotherapy group and radiotherapy alone group (P <0.05). There was no significant difference in the incidence of adverse reactions between the three groups (P> 0.05). Conclusion The curative effect of concurrent chemoradiotherapy for cervical cancer is better than that of neoadjuvant chemotherapy and radiotherapy alone, which is suitable for clinical application.