Effect of Id1 Knockdown on Formation of Osteolytic Bone Lesions by Prostate Cancer PC3 Cells In Vivo

• 作 者: 张正国 李宽新 张晓梅 方忠 熊伟 陈奇 陈文坚 李锋
• 机 构: DepartmentofOrthopaedics,DepartmentofOrthopaedics,DepartmentofHematology
• 出 处: Journal of Huazhong University of Science and Technology(Med
• 发表日期: 2012年3期
• 关键词: 前列腺癌 细胞株 病变 体内 甲状旁腺激素相关蛋白 短发夹RNA shRNA 慢病毒载体 inhibitor of differentiation 1bone

The formation of osteolytic bone lesions is a key process for osteolytic cancer to metastasize to the bone and is under the control of a set of transcription factors. Recently, the inhibitor of differentiation 1 (Id1) has been linked with angiogenesis, tu