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目的分析淮北市2003-2013年艾滋病患者接受抗病毒治疗效果。方法收集2003-2013年所有抗病毒治疗患者监测数据,统计分析其治疗前后CD4+T淋巴细胞计数、病毒载量、治疗维持及生存时间,评价其治疗效果。结果接受抗病毒治疗12月后CD4+T淋巴细胞计数均值有不同程度增长(P<0.001);治疗患者总体上病毒抑制率逐年提高(χ2=10.112,P=0.039);维持治疗3年、5年和7年生存率分别为91%、88%和87%。结论淮北市艾滋病抗病毒治疗效果显著,以全球基金/示范区模式推行重点地区的艾滋病综合防治,有力推动了抗病毒治疗各项措施的落实,减少了艾滋病传播。
Objective To analyze the effect of antivirus treatment on AIDS patients in Huaibei City from 2003 to 2013. Methods The surveillance data of all patients with antiviral therapy collected from 2003 to 2013 were collected. The counts of CD4 + T lymphocytes before and after treatment, viral load, treatment maintenance and survival time were statistically analyzed to evaluate the therapeutic effect. Results The mean CD4 + T lymphocyte count increased to some extent (P <0.001) after treated with antiviral therapy for 12 months. The viral suppression rate increased year by year (χ2 = 10.112, P = 0.039) The annual and 7-year survival rates were 91%, 88% and 87%, respectively. Conclusion The effect of HIV / AIDS treatment in Huaibei is significant. The implementation of integrated HIV / AIDS prevention and treatment in key areas under the Global Fund / Model Demonstration Zone has effectively promoted the implementation of various antiretroviral treatment measures and reduced the spread of AIDS.