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目的 :探讨新生儿 G- 6 - PD缺乏与性别和高胆红素血症的关系。方法 :采用 G- 6 - PD试纸法对 1999年 1月～ 2 0 0 2年 12月在我院产科出生的新生儿 2 380例进行 G- 6 - PD筛查并跟踪观察。结果 :男性新生儿 G- 6 - PD缺乏显著多于女性 (P <0 .0 1) ;男性 G- 6 - PD缺乏的新生儿高胆红素血症的发病率显著多于女性 (P <0 .0 1)。男女 G- 6 - PD缺乏的新生儿其父母籍贯以广西籍为主 (93% )。结论 :新生儿 G- 6 - PD缺乏存在性别差异 ,是新生儿高胆红素血症发病的主要病因之一
Objective: To investigate the relationship between neonatal G-6-PD deficiency and gender and hyperbilirubinemia. Methods: G - 6 - PD was screened and tracked by G - 6 - PD test paper on 2,380 newborns born in obstetrics from January 1999 to December 2002 in our hospital. Results: The incidence of G-6-PD deficiency in male neonates was significantly higher than that in women (P <0.01). The incidence of neonatal hyperbilirubinemia with G-6-PD deficiency was significantly higher in men than in women (P < 0 .0 1). Neonates born to men and women with G-6-PD were predominantly Guangxi natives (93%). Conclusion: There is a gender difference in neonatal G-6-PD deficiency, which is one of the major causes of neonatal hyperbilirubinemia