甲状腺功能亢进治疗前后呼吸肌功能及血清酶学变化的研究

来源 :华西医科大学学报 | 被引量 : 0次 | 上传用户:userbyf
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为了解甲状腺功能亢进对呼吸肌功能的影响,测定了60例Graves病伴甲状腺功能亢进症(简称甲亢)患者治疗前的甲状腺功能、血清酶、血钾、呼吸肌功能及肺功能,其中治疗后复查26例,并与20例正常对照组相比较。结果显示:60例甲亢患者治疗前T3、T4、FT4明显高于正常,而反映呼吸肌力的指标(FVC、PImax)及吸气肌储备功能(Pi/PImax)明显低于正常组。T3、FT4与呼吸肌力参数呈负相关,与Pi/PImax呈正相关。26例甲亢患者治疗前、后测值对比显示,治疗后在甲状腺功能改善同时,呼吸肌力明显增强,但甲亢患者无论治疗前、后血清酶、血钾、TSH皆无明显异常与改变。10例甲亢性心脏病(甲心病)与50例非甲心病甲亢患者甲状腺功能无明显差别,但甲心病患者呼吸肌力明显低于非甲心病患者。提示:甲亢可致呼吸肌力及其储备功能减退,甲亢治疗后,呼吸肌力随之增强;肺功能检测呼吸肌力的变化对预测甲心病有参考意义 In order to understand the effect of hyperthyroidism on respiratory muscle function, thyroid function, serum enzyme, serum potassium, respiratory muscle function and pulmonary function were measured in 60 patients with Graves’ disease complicated with hyperthyroidism (Hyperthyroidism) before and after treatment 26 cases were reviewed and compared with 20 normal controls. The results showed that T3, T4 and FT4 in 60 patients with hyperthyroidism before treatment were significantly higher than those in normal subjects, while those reflecting respiratory muscle strength (FVC, PImax) and inspiratory muscle reserve function (Pi / PImax) were significantly lower than those in normal group. T3, FT4 and respiratory muscle parameters were negatively correlated, and Pi / PImax was positively correlated. 26 cases of hyperthyroidism patients before and after treatment comparison showed that after treatment, thyroid function improved at the same time, respiratory muscle strength was significantly increased, but no matter before and after treatment of patients with hyperthyroidism, serum enzymes, serum potassium, TSH were no obvious abnormalities and changes. There were no significant differences in thyroid function between hyperthyroid heart disease (Hyperthyroidism) and hyperthyroidism (Hyperthyroidism) in 50 cases of non-Hyperthyroidism patients. However, the respiratory muscle strength of Hyperthyroidism patients was significantly lower than that of non-Hyperthyroidism patients. Hint: Hyperthyroidism can cause respiratory muscle strength and reserve function decline, hyperthyroidism treatment, respiratory muscle strength will be enhanced; changes in lung function test of respiratory muscle strength for the prediction of A reference significance
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