RhoA as a target to promote neuronal survival and axon regeneration

• 作 者: Jianli Hu Michael E. Seizer
• 机 构: ShrinersHospitalsforChildren,DepartmentofNeurology
• 出 处: 中国神经再生研究：英文版
• 发表日期: 2017年4期
• 基金项目: This study was supported by ROI-NS092876 （NIH, MES, PI）, SHC-85400 （Shriners Research Foundation, MES, PI）, SHC-85220（Shriners Research Foundation, MES, PI） and SHC-84293 （Shriners Research Foundation

Paralysis following spinal cord injury(SCI) is due to failure of axonal regeneration. It is believed that the capacities of neurons to regrow their axons are due partly to their intrinsic characteristics, which in turn are greatly influenced by several ty