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目的研究18F-氟脱氧葡萄糖(18F-FDG)符合线路显像对妇科复发性卵巢癌治疗方案的影响。方法对75例怀疑复发的卵巢癌患者,行85例次全身18F-FDG符合线路显像,并与近期B超、CT、MRI检查结果相比较。复发诊断根据病理、血CA125监测及随访结果确诊。结果 85例次检查中,阳性61例次,阴性24例次。阳性者证实全部为复发;阴性者中,1例CA125升高,后经随访确诊为复发,1例3次18F-FDG显像阴性,B超及CT等检查亦无复发证据(考虑肠管粘连),后因反复腹痛,行剖腹探查,明确为肠转移,行肠切除术。18F-FDG符合线路显像监测复发的准确率、灵敏度、特异度分别为97.67%、96.83%、100%,而B超、CT、MRI检查的准确率分别为70.25%、85.24%、44.34%。结论 18F-FDG符合线路显像较其他影像学检查能更早并准确发现可疑病灶,使患者获得早发现、早治疗的机会。
Objective To investigate the effect of 18F-FDG coincidence imaging on the treatment of gynecological recurrent ovarian cancer. Methods Totally 75 cases of ovarian cancer patients suspected to have recurred were enrolled in this study. All the patients underwent 18F-FDG coincidence imaging and compared with the results of B ultrasound, CT and MRI. Diagnosis of recurrence is based on pathology, blood CA125 monitoring and follow-up results confirmed. Results 85 cases were examined, the positive 61 cases, negative 24 cases. Positive patients confirmed all recurrence; negative ones, one case of CA125 increased after the follow-up diagnosis of recurrence, 1 case of 3 negative 18F-FDG imaging, B ultrasound and CT examination no evidence of recurrence (consider intestinal adhesions) , After repeated abdominal pain, laparotomy exploration, specifically for intestinal metastasis, bowel resection. The accuracy, sensitivity and specificity of 18F-FDG coincidence imaging were 97.67%, 96.83% and 100% respectively. The accuracy rates of ultrasound, CT and MRI were 70.25%, 85.24% and 44.34% respectively. Conclusions 18F-FDG coincidence imaging can detect suspicious lesions earlier than other imaging examinations and make the patients get the chance of early detection and early treatment.