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目的:探讨麻痹性痴呆合并艾滋病患者的临床特点。方法:选取2012年3月至2015年2月广东三九脑科医院收治的6例麻痹性痴呆合并艾滋病患者的临床表现和实验室检查进行回顾性分析。结果:麻痹性痴呆合并艾滋病患者平均年龄36.5岁,均先后出现不同程度的记忆力减弱和性格改变,答非所问,言语不清,反应迟钝,定向力下降等痴呆症状。经过系统治疗后3例患者基本能够恢复正常生活和工作。3例有轻度改善。结论:在艾滋病患者中,麻痹性痴呆可发生在青壮年患者中,及时诊断和足量的驱梅治疗可改善神经系统症状,同时需要注意有无同时合并艾滋病脑病。
Objective: To investigate the clinical features of patients with AIDS and AIDS complicated with paralytic dementia. Methods: Six cases of paralytic dementia with AIDS in our hospital from March 2012 to February 2015 were retrospectively analyzed. Results: The mean age of patients with paralytic dementia complicated with AIDS was 36.5 years old. There were some dementia symptoms such as weakened memory and personality change in different degrees afterwards, nonresponsiveness, unclear speech, unresponsiveness and decreased orientation force. After systematic treatment, 3 patients can basically resume normal life and work. 3 patients had mild improvement. CONCLUSIONS: Paralytic dementia can occur in adolescent patients with AIDS, and prompt diagnosis and adequate expelment of the plum may improve neurological symptoms. At the same time, attention should be paid to whether there is any combination of AIDS encephalopathy.