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目的探讨宫腔镜手术前后机体红细胞免疫和T淋巴细胞亚群免疫功能的变化,为临床治疗及预后评价提供理论依据。方法以红细胞C3b受体花环率、红细胞免疫复合物花环率、肿瘤红细胞花环率及CD3、CD4、CD8细胞作为观测指标,测定汕头大学医学院第二附属医院2001年3月至2005年1月间收治的38例宫腔镜下施术患者术前和术后第1天、第3天的免疫指标变化,并与对照组进行比较。结果宫腔镜下施术患者术后第1天的上述免疫指标虽有轻度下降,但差异没有显著性意义,且术后第3天迅速恢复。结论宫腔镜患者手术前后红细胞免疫功能和T淋巴细胞亚群免疫功能没有明显变化,是患者手术后能够迅速恢复的免疫依据。
Objective To investigate the changes of red blood cell immunity and T lymphocyte subsets immunity before and after hysteroscopic surgery, and to provide a theoretical basis for clinical treatment and prognosis evaluation. Methods The rate of erythrocyte C3b rosette, rosette of erythrocyte immune complex, rate of erythrocyte rosette, CD3, CD4 and CD8 cells were taken as the observation indexes. The second affiliated hospital of Shantou University Medical College was measured from March 2001 to January 2005 38 cases of hysteroscopic surgery patients received preoperative and postoperative 1 day, 3 days of immune changes, and compared with the control group. Results The hysteroscopic surgery patients on the first day after the operation although the above immune index decreased slightly, but the difference was not significant, and the rapid recovery after 3 days. Conclusion There is no significant change in the immune function of erythrocyte and T lymphocyte subsets before and after hysteroscopy in patients with hysteroscopy, which is the basis of immunization of patients with rapid recovery after surgery.