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目的观察半乳凝素-3(Gal-3)在垂体泌乳素腺瘤中的表达情况。方法采用免疫组织化学方法,测定16例侵袭性垂体泌乳素腺瘤和16例非侵袭性垂体泌乳素腺瘤中Gal-3的表达水平。结果在侵袭性垂体泌乳素腺瘤和非侵袭性垂体泌乳素腺瘤中均有Gal-3的表达,其中侵袭性垂体泌乳素腺瘤中Gal-3的表达水平明显高于非侵袭性垂体泌乳素腺瘤(P<0.05雪。结论Gal-3增高可能与垂体泌乳素腺瘤的侵袭性有关。
Objective To observe the expression of galectin-3 (Gal-3) in pituitary prolactinomas. Methods Immunohistochemical method was used to determine the expression of Gal-3 in 16 cases of invasive pituitary prolactinoma and 16 cases of non-invasive pituitary prolactinoma. Results The expression of Gal-3 in both invasive pituitary prolactinoma and non-invasive pituitary prolactinoma was significantly higher than that in non-invasive pituitary gland (P <0.05 snow. Conclusion Gal-3 increased may be related to the aggressiveness of pituitary prolactinoma.