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目的:观察欣普贝生用于足月妊娠胎膜早破促宫颈成熟及引产的有效性和安全性。方法:选择2009年1月～2010年1月常州市妇幼保健院38例足月妊娠胎膜早破的孕妇,所有孕妇产前阴道后穹窿放置1枚欣普贝生,分析用药前后宫颈Bishop评分、临产情况、催产效果、母儿并发症的发生率。结果:给药后促宫颈成熟有效率86.84%,显效率78.94%,引产成功率81.58%,剖宫产率23.68%,发生宫缩过强2例,发生率为5.26%,经及时处理后转归良好。结论:欣普贝生用于足月妊娠胎膜早破引产安全有效,不良反应小,对母儿无明显不良影响。
OBJECTIVE: To observe the efficacy and safety of Hippocampus in term pregnancy-induced premature rupture of membranes for cervical ripening and induction of labor. Methods: From January 2009 to January 2010, 38 pregnant women with full-term premature rupture of membranes in Changzhou Maternal and Child Health Care Hospital were enrolled. One prenatal vaginal fornix was placed in each pregnant woman. The Bishop’s cervical score , Labor conditions, oxytocin effects, maternal and child complications. Results: The effective rate of cervical ripening was 86.84%, the effective rate was 78.94%, the successful rate of induced labor was 81.58%, the rate of cesarean section was 23.68%, and the incidence of uterine contractions was strong in 2 cases (5.26%). Go good. CONCLUSIONS: The drug is safe and effective for gestational premature rupture of abortion in patients with term pregnancy. The adverse reaction is small, and there is no obvious adverse effect on the mother and child.