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目的:研究经子宫动脉药物灌注栓塞治疗异位妊娠的疗效及应用价值。方法:对19例明确诊断异位妊娠的患者行超选择子宫动脉造影后经导管注入甲氨蝶呤(MTX),并用可吸收性明胶海绵颗粒对子宫动脉行完全性栓塞。对其中16例患者术后第3次月经干净后行子宫输卵管造影。结果:18例患者经治疗后,血清人绒毛膜促性腺激素(HCG)水平下降至正常值(<50 mIU/ml),1例宫角妊娠,因术后血HCG上升行手术治疗。子宫输卵管造影16例,显示患侧输卵管通畅14例。结论:经子宫动脉药物灌注栓塞是治疗输卵管妊娠的有效方法,可有效保留卵巢及输卵管的生理及解剖功能。
Objective: To study the curative effect and application value of uterine arterial drug embolization in the treatment of ectopic pregnancy. Methods: Nineteen patients with definite diagnosis of ectopic pregnancy underwent transcatheter arterial injection of methotrexate (MTX) after superselective uterine artery angiography. Complete embolization of uterine artery with absorbable gelatin sponge particles was performed. Of the 16 patients after the first 3 menstrual clean hysterosalpingography. Results: Serum human chorionic gonadotropin (HCG) levels decreased to normal values (<50 mIU / ml) in 18 patients after treatment, and 1 case had pregnancy with uterine hormones. Surgical treatment of postoperative HCG rise was performed. Hysterosalpingography in 16 cases, showing ipsilateral tubal patency in 14 cases. CONCLUSION: Transcatheter arterial infusion of uterine artery is an effective method for the treatment of tubal pregnancy, which can effectively preserve the physiology and anatomy of the ovary and oviduct.