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目的：探讨米索前列醇用于足月妊娠引产的安全性及效果。方法：将１００ 例有引产指征的初产单胎头位、无宫缩的足月孕妇随机分成两组：实验组（５０ 例）用米索前列醇２５μｇ 阴道上药，每３ 小时１ 次直至临产；对照组（５０ 例）用催产素静滴。结果：实验组诱发宫缩及第一产程时间明显少于对照组（Ｐ＜ ０．０５），两组妊娠结局基本一致，仅米索组宫缩过频致胎儿宫内窘迫发生率较高（１８％ ），对照组１２％ （Ｐ＜ ０．０５）。结论：阴道放置米索前列醇用于足月孕引产能有效促宫颈成熟、诱发宫缩。若规范使用，是一种经济、安全的引产方法。
Objective: To investigate the safety and efficacy of misoprostol for induction of labor during term pregnancy. Methods: 100 primiparous primiparous women with gestational age without gestational contractions were randomly divided into two groups: experimental group (n = 50) received vaginal administration of misoprostol 25 μg once every 3 hours Until labor; control group (50 patients) intravenous infusion of oxytocin. Results: The experimental group induced contractions and the first stage of labor was significantly less than the control group (P <0.05), the two groups of pregnancy was basically the same, only misoprostol overfrequency fetal distress was higher 18%), control group 12% (P <0.05). Conclusion: vaginal misoprostol for induction of full-term labor induction of cervical ripening, induced contractions. If the standard use, is an economical, safe method of induction of labor.