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用亲和层析法纯化人卵巢抗原、建立ＥＬＩＳＡ间接法检测不孕、流产患者血清中三种Ｉｇ类抗卵巢抗体。结果表明：不孕、流产患者血清中ＩｇＧ、ＩｇＡ、ＩｇＭ三类抗卵巢抗体的水平与阳性率，均明显高于对照组（Ｐ＜０．０１）。提示此类抗体的检测，有助于了解不孕、流产的病因。
Human ovarian antigens were purified by affinity chromatography and indirect ELISA was used to detect three kinds of anti-ovarian antibodies in serum of infertility and abortion patients. The results showed that the level and the positive rate of three anti-ovarian antibodies (IgG, IgA and IgM) in the serum of infertility and abortion patients were significantly higher than those of the control group (P <0.01). Tip detection of such antibodies, helps to understand the causes of infertility, miscarriage.