Human norepinephrine transporter gene

• 作 者: 郭礼和 朱丽华 黄芳 AntnonyC.W.Tam 叶增产 费俭 张孝勇 DominicMan-KitLam
• 机 构: Shanghai Institute of Cell Biology, Chinese Academy of Sciences, Shanghai 200031, China),Shanghai In
• 出 处: Chinese Science Bulletin
• 发表日期: 1995年17期
• 关键词: transporter norepinephrine synaptic terminals cloned cleft genomic subsequent cl

Norepinephrine (NE) is a catecholamine neurotransmitter in postganglionic sympatheticnerves and within the central nervous system. In noradrenergic neurons, synaptictransmission includes three stepst release of NE into the synaptic cleft, interaction with apostsynaptic receptor, and subsequent removal from the cleft into pre-synaptic terminals or glialcells. This reaccumulation process is catalyzed by sodium-dependent NE transporter (NET).

Norepinephrine (NE) is a catecholamine neurotransmitter in postganglionic sympathetic nerves and within the central nervous system. In noradrenergic neurons, synaptic transmission includes three stepst release of NE into the synaptic cleft, interaction with apostsynaptic receptor, and subsequent removal from the cleft into pre-synaptic terminals or glialcells. This reaccumulation process is catalyzed by sodium-dependent NE transporter (NET).