The effect on the Pregnancy Rate in Patients with Endometriosis and Infertility

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Objective:To compare infertility patients who have no endometriosis (Controls) with infertility patients who have Endometriosis (Subjects) and see if the Pregnancy Rate of the Control patients are more than the Subject ones.  Design:Retrospective Analysis.  Setting:Medical Reproductive Centre, Union Hospital, Wuhan,China.  Methods:Patients who were chosen randomly, came for treatment between the year 2008 to 2010.58 patients were chosen as those having Endometriosis and infertility (Subjects) and 53 patients were chosen as Controls, therefore having infertility not related to endometriosis.  The 58 Subjects and 53 Controls were grouped as per their Age,Diagnosis, History of Surgery, Years of Infertility, Process of IVF, Dose of Gn, Days of Gn, Number of Oocytes pick-up, Number of Normal Fertilisation (2PN), Embryo Grade.  The Pregnancy Result of each of these groups were noted and compared with eachother.  Results:Out of the 58 Subjects, there were 22 pregnancy results positive.11 patients had 1 baby.5 patients had Twins pregnancies, out of which 2 patients delivered 2 live babies and 3 patients delivered 1 live baby.5 patients had an abortion.1 patient had an ectopic pregnancy.No ET was done for 10 patients as 4 patients had Fluid in Uterus, 4 patients had OHSS, 2 patients had No Oocytes for pick-up.  Out of the 53 Controls,there were 21 pregnancy res ults positive.15 patients had 1 baby.4 patients had twins.1 patient aborted.1 patient had an ectopic pregnancy.No ET was done for 3 patients as 1 patient had fever and 2 patients had OHSS.  Conclusion: The Subjects gave a better outcome for the Age group, Diagnosis of patients group and the Number of Normal Fertilisation group.  An overall same results for both Subjects and Controls was for the Patients’ History of Surgery group, Years of Infertility group, Process of IVF group, Days of Gn group,Number of Oocytes group, Embryo grade group.  The Controls gave a better outcome for the Dose of Gn group.  So,on overall both Subjects and Controls gave the same result and it can be concluded that patients who have Endometriosis and Infertility have the same overall Pregnancy Rate as patients who have Infertility with no endometriosis.
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