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Purpose:The purpose of this Meta analysis study was to evaluate whether the use of 18F-FDG PET can lead to accurate diagnosis of Small Cell Lung Cancer．
Materials and methods:A Meta analysis study was designed to examine the role of 18F-FDG PET(PET or Hybrid PET/CT)in the diagnosis of small cell lung cancer．Nine eligible studies were selected with a total of 644 patients(409 men，235 women，age range 30-89 years)with SCLC．The sensitivity,specificity and diagnostic accuracy of 18F-FDG PET,and 18F-FDG PET/CT was calculated using Meta-Disc software version 1.4(Hospital Ramon Cajal)and SAS version 8.0(SPSS，Inc，Chicago，IL)．
Results:The sensitivity of 18F-FDG PET was found to be 80.8％and had a specificity of 93.1％．The Summary Receiver Operating Characteristics curve shows a diagnostic accuracy Q* 88.68％,AUC of 0.9473．
The sensitivity of the studies which used 18F-FDG PET in the diagnosis of SCLC was found to be 89.8％and specificity was 93.8％．The diagnostic accuracy of 18F-FDG PET in the diagnosis of SCLC as shown in the sROC curve was Q* 91.93％，AUC of 0.9697．
The sensitivity of the studies which used 18F-FDG PET/CT in the diagnosis of SCLC was found to be 86.9％and specificity was found to be 92.6％．The diagnostic accuracy of 18F-FDG PET/CT in the diagnosis of SCLC as shown in the sROC curve was found to be Q* 88.70％ and AUC is 0.9474．
Conclusion:The results of this study shows that 18F-FDG PET and 18F-FDG PET/CT have a high sensitivity,specificity and diagnostic accuracy in the diagnosis of SCLC．18F-FDG PET can be used as a standard diagnostic tool of small cell lung cancer．
Materials and methods:A Meta analysis study was designed to examine the role of 18F-FDG PET(PET or Hybrid PET/CT)in the diagnosis of small cell lung cancer．Nine eligible studies were selected with a total of 644 patients(409 men，235 women，age range 30-89 years)with SCLC．The sensitivity,specificity and diagnostic accuracy of 18F-FDG PET,and 18F-FDG PET/CT was calculated using Meta-Disc software version 1.4(Hospital Ramon Cajal)and SAS version 8.0(SPSS，Inc，Chicago，IL)．
Results:The sensitivity of 18F-FDG PET was found to be 80.8％and had a specificity of 93.1％．The Summary Receiver Operating Characteristics curve shows a diagnostic accuracy Q* 88.68％,AUC of 0.9473．
The sensitivity of the studies which used 18F-FDG PET in the diagnosis of SCLC was found to be 89.8％and specificity was 93.8％．The diagnostic accuracy of 18F-FDG PET in the diagnosis of SCLC as shown in the sROC curve was Q* 91.93％，AUC of 0.9697．
The sensitivity of the studies which used 18F-FDG PET/CT in the diagnosis of SCLC was found to be 86.9％and specificity was found to be 92.6％．The diagnostic accuracy of 18F-FDG PET/CT in the diagnosis of SCLC as shown in the sROC curve was found to be Q* 88.70％ and AUC is 0.9474．
Conclusion:The results of this study shows that 18F-FDG PET and 18F-FDG PET/CT have a high sensitivity,specificity and diagnostic accuracy in the diagnosis of SCLC．18F-FDG PET can be used as a standard diagnostic tool of small cell lung cancer．