高原重型颅脑损伤患者脑氧代谢变化特点及乌司他定的干预作用

来源 :中华医学会第10次全国重症医学大会 | 被引量 : 0次 | 上传用户:windlian
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目的 探讨高原地区重型颅脑损伤脑氧变化特点及无乌司他丁对其的干预作用 方法 采用随机数字法将60 例高原地区重型颅脑损伤患者分为乌司他丁组(U 组)和对照组(C组),每组患者均在伤侧或受伤较重一侧行颈内静脉逆行穿刺置管,导管尖端至颈静脉球部,伤后第1,2,3,4,5 天上午8 点采集颈静脉球部血、同步抽取桡动脉血作血气分析(血气分析仪,GEM3000,美国产),记录动脉血氧分压(PaO2)、动脉血氧饱和度(SaO2)、颈内静脉血氧分压(PjvO2)、颈内静脉血氧饱和度(SjvO2)、血红蛋白(Hb)等指标,并计算动脉颈内静脉血氧含量差(A-VDO2)、脑氧摄取率(CERO2).
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