High-dimensional Cell Image Data Analysis in Drug Discovery

来源 :The Third IMS-China International Conference on Statistics a | 被引量 : 0次 | 上传用户:wangaimin143074
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  In high-content screening (HCS) assay, the cell images in each well of multi-well plates are captured and multiple cell features (i.e., cell counts, size, shape, intensity,texture, overlap of colors) are extracted from images.The high-dimensional features/parameters provide more representatives of biological models that allow phenotype definition and pathway analysis for both compound and target screenings,and for analysis of mechanisms of actions,
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