Elastomers with controlled release potential for applications in cardiovascular disease

来源 :Fourth Symposium on Innovative Polymers for Controlled Deliv | 被引量 : 0次 | 上传用户：ywh831002

【摘要】

：

Thermoplastic,biodegradable elastomers have been developed using polyurethane chemistry with a variety of soft segment diols or chain-extending diamines to introduce hydrolytic and enzymatic lability[

【作者】

：

Xinzhu Gu Yasumoto Matsumura Bing Wang Ying Tang Souvik Roy William R.Wagner

【机构】

：

McGowan Institute for Regenerative Medicine,University of Pittsburgh,Pittsburgh 15219,USA

【出处】

：

Fourth Symposium on Innovative Polymers for Controlled Deliv

【发表日期】

：

2016年11期

【关键词】

：

cardiovascular elastomer myocardial infarction gene delivery

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

其他文献

Targeted polymeric nanoparticles:From discovery to clinical trials

A variety of organic and inorganic materials have been utilized to generate nanoparticles for drug delivery applications,including polymeric nanoparticles,dendrimers,nanoshells,liposomes,nucleic acid

会议

nanoparticletargeted therapydrug deliverybiogradable polymers

Controlled local drug delivery by various thermo-responsive hydrogels

For in situ thermo-sensitive hydrogel,it is a big challenge to achieve high drug loading,long-term local retention and effective drug release simultaneously.Firstly,we investigated thermo-sensitive Pl

会议

controlled drug deliverythermo-responsivehydrogellocal injection

Multivalent nanosystems as anti-inflammatory and antiviral drugs

会议

Engineering intracellular delivery nanocarriers and nanoreactors from oxidation-responsive polymerso

Reactive oxygen species (ROS) and oxidative stress are implicated in various physiological and pathological processes and this feature provides a vital biochemical basis for designing novel therapeuti

会议

oxidation-responsivepolymersomesbilayer permeabilityin vivo nanoreactors

Bioactive glycopolypeptide self-assembled biohybrid nanomaterials

The field of synthetic polypeptides has seen many significant advances in recent years,including studies on block and hybrid copolypeptides that form vesicles,fibrils,and other structures with potenti

会议

block copolymersself-assemblyglycopolymerspolymersomes

Multifunctional unimolecular micelles for targeted cancer therapies

Drug nanocarriers are of great interest in targeted cancer therapy due to their passive (via the enhanced permeability and retention (EPR) effect) and active (via cell-specific ligand conjugation) tum

会议

unimolecular micellestargeted cancer therapiesdrug nanocarriercontrolled rele

Functional conjugated polymers for antibacterial and antitumor applications

Water-soluble conjugated polymers (CPs) provide a unique platform for chemical and biological sensors in view of their optical signal amplification effect.Our recent studies showed that CPs/DNA comple

会议

conjugated polymersfluorescenceantibacteriaantitumor

Delivery of bio-macromolecular therapeutics,an ideal stage for displaying the beauty of chemical art

While biologic medicines have been rapidly growing since 1980s,the advances of their administrating technologies are utterly behind.Despite of intensive research efforts in sustained-release injection

会议

delivery of biologicsmicrospheresmicroneedlespolymersomessynthetic carriers

Monitoring and modulating drug targeting to tumors and metastases

Nanomedicines are 1-100(0) nm-sized carrier materials designed to improve the biodistribution and the target site accumulation of systemically administered (chemo-) therapeutic drugs.By delivering dru

会议

nanomedicinetumor targetingEPRimaging

Light/ROS-responsive bilirubin nanoparticles as a nanomedicine for anticancer and anti-inflammation

Although stimuli-responsive materials hold potential for use as drug delivery carriers for treating cancers,their clinical translation has been limited.Ideally,materials used for the purpose should be

会议

bilirubinnanoparticlesnanomedicinestimuli-responsivenessinflammatory disease

Elastomers with controlled release potential for applications in cardiovascular disease

其他学术论文