【摘 要】
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Objective: Macrophages (M) can polarize into pro-inflammatory M1 or anti-inflammatory M2 phenotypes in response to different environment signals.Some autoimmune diseases are characterized by the impai
【机 构】
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Department of Hematology, Qilu Hospital, Shandong University, Jinan, China
【出 处】
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中华医学会第15次全国血栓与止血学术会议
论文部分内容阅读
Objective: Macrophages (M) can polarize into pro-inflammatory M1 or anti-inflammatory M2 phenotypes in response to different environment signals.Some autoimmune diseases are characterized by the impairment of macrophage polarization, but there is noprevious report referred to immune thrombocytopenia (ITP).One study showed that all-trans retinoic acid (ATRA) combined with IL-4 dramatically induced M2 differentiation in murine.However, the effect of ATRA on macrophage polarization in patients with ITP has not yet been reported.
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