A Multifunctional Fluorescent Chelator for Targeting Metal-Induced Aβ Aggregation

• 作 者: TaoYang[1]JianLuo[1]LiuYang[1]ChengYao[1]XiaohuiWang[2]
• 机 构: College of Sciences,Nanjing Tech University,Nanjing,211816
• 出 处: 第九届全国无机化学学术会议
• 发表日期: 2015年期

　　Alzheimer's disease(AD)is the most common form of dementia.Amyloid β(Aβ),a peptide of 40 or 42 amino acids,plays a key role in AD pathology.The aggregation of Aβ is one of the neuropathological hallmarks of AD.While the aggregates,especially soluble oligomers,spark the neuronal dysfunction and cell death.