Synthesis of a Novel Quinoline Skeleton Introduced Cationic Polyfluorene Derivative for Multimodal A

• 作 者: 孙含;
• 机 构: Institute of Chemistry,Chinese Academy of Sciences
• 出 处: 中国化学会生物物理化学专业委员会第四届全国生物物理化学会议
• 发表日期: 2016年期

　　A new functional polyfluorene derivative containing quinoline skeleton and quarternary ammonium groups(QAGs)modified side chains(PFPQ)was synthesized and characterized.The multimodal antimicrobial effect toward Gram-negative E.coli.was achieved by the dark toxicity resulting from quinoline skeleton,and QAGs and light toxicity resulting from reactive oxygen species(ROS)produced by the main backbone of PFPQ under white light.