Alkaloids as Drug Leads-A Predictive Structural and Biodiversity-based Analysis

来源 :第十四届全国中药和天然药物学术研讨会暨第十三届中药全球化联盟大会 | 被引量 : 0次 | 上传用户:walter1i
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The process of drug discovery and development particularly that of natural products, has evolved markedly over the last 30 years into increasingly formulaic approaches.As a major class of natural products initially discovered and used as early as 4000 years ago, alkaloids and the species they are derived from have been used worldwide as a source of remedies to treat a wide variety of illnesses.Yet, a tremendously wide discrepancy between their historical significance and their occurrence in modern drug development exists.Are alkaloids underrepresented in modern medicine?
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