Noninvasiveassessmentofatherosclerosisatcarotid,cerebraland coronaryarteriesusinghigh-pit

• 作 者: chenwang
• 机 构: Xuanwuhospitalcapitalmedicaluniversity
• 出 处: 中华放射学学术大会2016、中华医学会第23次全国放射学学术大会暨中华医学会第24次全国影像技术学术大会
• 发表日期: 2016年5期
• 关键词: diabetesmellitus dual-sourceCTA acuteischemicstroke atherosclerosis

　　Purpose:Toevaluatethecharacteristicofatherosclerosisatcarotid,cerebralandcoronaryarteriesinpatientsafteracute ischemicstroke(AIS)withandwithouttype-2diabetesmellitususinghigh-pitchdual-sourceCTA. Methods:77patientsafterAISundergoinghigh-pithcombinedcoronaryandcarotid-cerebralCTAwithin2weeksweredivided intotwogroupsbasedonthepresenceoftype-2diabetesornot.Curvedplanarreformatting(CPR),maximumintensity projection(MIP),multiplanarreformatting(MPR)andvolumerendering(VR)imageswereusedtoevaluatetheatherosclerosisof carotid,cerebralandcoronaryarteries.Obstructionorstenosisgreaterthan50%wasclassifiedassignificantstenosis.Coronary arterycalciumscores(CACS),aortacalciumscores,carotidbifurcationcalciumscores,carotidsiphoncalciumscoreswere quantifiedsemiautomaticallybycalculatingAgastonscoreonnon-enhancedimages.Differencebetweenthetwogroupswas compared.Riskfactorssuchasage,gender,hypertension,dyslipidemia,historyofcerebrovasculardiseaseandcoronaryartery diseasewerecomparedaswell. Results:Amongthe77subjects(58male,19female,meanage59.4±10.8years),36.4%(28cases)haddiabetes.Therewasno statisticaldifferenceontheprevalenceofsignificantstenosisincoronary,carotidandcerebralarteriesbetweenthetwogroups. Thecourseofcerebrovasculardisease,rightcoronaryarterycalciumsoresandcarotidbifurcationcalciumscoresweredifferent betweenthetwogroups(P<0.05). Conclusions:InAISpatients,type-2diabetesisrelatedtosomeatherosclerosisfeaturesbutnottotheseverityofstenosisat coronary,carotidorcerebralarteries