Heat-shock Reveals Common Features in Misfolded Proteins and a New Hul5 Ubiquitin Ligase QC Pathway

来源 :第七届中国蛋白质组学大会暨第三届国际蛋白质组学论坛 | 被引量 : 0次 | 上传用户：xsnxj112

【摘要】

：

The ubiquitin proteasome system plays a major role in the clearance of misfolded proteins.Quantitative MS analysis revealed that heat-shock induces the ubiquity

【作者】

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Mayor Thibault

【机构】

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UniversityofBritishColumbia

【出处】

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第七届中国蛋白质组学大会暨第三届国际蛋白质组学论坛

【发表日期】

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2011年4期

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The ubiquitin proteasome system plays a major role in the clearance of misfolded proteins.Quantitative MS analysis revealed that heat-shock induces the ubiquitylation of mainly cytosolic misfolded proteins and that several unique structural features are shared among these proteins.

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Heat-shock Reveals Common Features in Misfolded Proteins and a New Hul5 Ubiquitin Ligase QC Pathway

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