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  5. Enzyme-Responsive Dendritic Polymer-Drug Conjugates Based Nanoscale Drug Delivery Systems for Cancer

Enzyme-Responsive Dendritic Polymer-Drug Conjugates Based Nanoscale Drug Delivery Systems for Cancer

来源 :The 6th International Conference on Nanoscience and Technolo | 被引量 : 0次 | 上传用户：delicioussmoke
【摘 要】
：
　　Stimuli-responsive dendritic polymer-drug conjugates have presented significant potential for cancer therapy.In our studies,we synthesized and characterized
【作 者】
：
KuiLuo;ChengyuanZhang;DayiPan;ZhongweiGu; 
【机 构】
：
National Engineering Research Center for Biomaterials,Sichuan University,Chengdu 610064,China
【出 处】
：
The 6th International Conference on Nanoscience and Technolo
【发表日期】
：
2015年期
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　　Stimuli-responsive dendritic polymer-drug conjugates have presented significant potential for cancer therapy.In our studies,we synthesized and characterized a serial of enzyme-responsive dendritic polymer-GFLG-drug conjugates[1-2],including PEGylated peptide dendrimer-GFLG-drug conjugates and dendritic poly[N-(2-hydroxypropyl)methacrylamide]-GFLG-drug conjugates(polyHPMA-GFLG-drug conjugates),and their potential as biodegradable and environment-responsive nanoscale drug delivery vehicles for cancer therapy.
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