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This paper introduces the physics-based time-space RBFs for dynamic interpolation,which have potential to be used in data processing and reconstruction of movie and animation.This study considers the diffusion-type dynamic interpolation data.The time-space fundamental solution and its variants of diffusion equations are employed as interpolation basis functions,The special technique is introduced to handle singularities at the origin.Several benchmark examples are provided to test the accuracy and efficiency of the present method for dynamic interpolation of diffusion data.