PAK5-mediated E47 phosphorylation promotes epithelial-mesenchymal transition and metastasis of colon

来源 :中国细胞生物学学会2015年全国学术大会 | 被引量 : 0次 | 上传用户：aaajansen

【摘要】

：

The p2 l-activated kinase 5 (PAK5) is overexpressed in advanced cancer and the transcription factor E47 is a direct repressor of E-cadherin and inducer of epithelial-mesenchymal transition (EMT).

【作者】

：

Ge Zhu Xiaodong Li Bingyu Guo Qiang Ke Feng Li

【机构】

：

Department of Cell Biology, Key Laboratory of Cell Biology, Ministry of Public Health of China, and

【出处】

：

中国细胞生物学学会2015年全国学术大会

【发表日期】

：

2015年4期

【关键词】

：

E47 PAK5 EMT colon cancer metastasis

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　　The p2 l-activated kinase 5 (PAK5) is overexpressed in advanced cancer and the transcription factor E47 is a direct repressor of E-cadherin and inducer of epithelial-mesenchymal transition (EMT).

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PAK5-mediated E47 phosphorylation promotes epithelial-mesenchymal transition and metastasis of colon

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