【摘 要】
：
目的 本研究通过对多囊卵巢综合征(PCOS)患者生活质量、心理健康状况和性生活情况的问卷调查,分析其与非PCOS不孕患者、正常人的差异,并研究其与PCOS主要表现如多毛、痤疮、肥胖、不孕、月经失调、高雄激素血症等的联系.方法 选取PCOS患者44例(其中不孕患者32例),同期随机选取单纯输卵管因素和/或男方因素导致的不孕不育患者34例,正常对照组33例.三组研究对象均独立完成相关问卷调查：心理健康
【机 构】
：
福建医科大学附属协和医院妇产科 350001
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目的 本研究通过对多囊卵巢综合征(PCOS)患者生活质量、心理健康状况和性生活情况的问卷调查,分析其与非PCOS不孕患者、正常人的差异,并研究其与PCOS主要表现如多毛、痤疮、肥胖、不孕、月经失调、高雄激素血症等的联系.方法 选取PCOS患者44例(其中不孕患者32例),同期随机选取单纯输卵管因素和/或男方因素导致的不孕不育患者34例,正常对照组33例.三组研究对象均独立完成相关问卷调查：心理健康状况(SCL-90)、性生活情况(VAS),PCOS组还需完成多囊卵巢综合征生活质量问卷修订版(MPCOSQ).结果 1.PCOS组与正常组对比：PCOS组强迫、人际敏感、抑郁、焦虑、敌对等因子分值及多毛对性生活的影响度均较高；性生活满意度、性感程度明显低于正常组.2.PCOS不孕组与非PCOS不孕组对比：PCOS不孕组强迫、人际敏感、抑郁等因子分值及多毛对性生活影响度均较高；自我评价较不性感.3.PCOS患者生活质量较低,患者最关注不孕方面,其次是月经的可预测性、体重.4.BMI与MPCOSQ中体重负相关,与SCL-90中躯体化正相关,与VAS中自我评价性感程度负相关；多毛(mFG评分)与MPCOSQ中体毛负相关,与SCL-90中躯体化正相关,与VAS中多毛影响度正相关；痤疮(GAGS评分)与MPCOSQ中痤疮负相关；血清雄激素与MPCOSQ中体毛负相关,与VAS中性欲正相关.5.MPCOSQ中不孕因子在不孕症组与无不孕症组之间有显著性差异,体重因子在肥胖组与非肥胖组之间差异有显著性意义,合并高雄激素血症者的性欲明显高于无高雄激素血症者.结论 PCOS患者患心理疾病的风险明显高于非PCOS不孕组和正常对照组,PCOS患者本身就存在心理障碍问题.PCOS患者的生活质量较低,患者关注的问题依次是不孕、月经预测性和体重.另外PCOS患者的性生活满意度也明显下降,多毛对性生活影响度较大,性感程度受影响.治疗PCOS相关临床症状可以改善PCOS患者的心理状态、生活质量及性生活.
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