Synthesis and Structural Characterization of Two Epimers Driven from 20(S)-Protopanaxadiol

• 作 者: MengQing-Guo[1]BiYi[1]TanWen-Juan[2]ZhangXi-Yue[1]HuXin-Yue[1]YangFan[1]BaiGuo-Jing[1]ZhuWei-Wei[1]CaiYi[1]
• 机 构: Schooolof Pharmacy Yantai University Yantai 264005
• 出 处: 全国药物化学学术会议暨第四届中英药物化学学术会议
• 发表日期: 2013年期

　　Two epimers,(20S,24R)-epoxy dammarane-3β,12β,25-triol(3)and(20S,24S)-epoxy dammarane-3β,12β,25-triol(4)were prepared from 20(S)-protopanaxadiol,which were confirmed by ESI-MS,NMR,and X-ray single-crystal diffraction.The results indicate the configuration of C-24 of 3 and 4 are R-form and S-form,respectively.