心脏移植受体应用巴利昔单抗免疫诱导的临床经验

来源 :第二十四届长城国际心脏病学会议、亚太心脏大会暨国际心血管病预防与康复会议(The 24th Great Wall Int | 被引量 : 0次 | 上传用户:shenqian1015
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目的:回顾性分析经巴利昔单抗免疫诱导后心脏移植受体延迟使用钙调磷酸酶抑制剂(CNIs)有无增加排异反应发生率.方法:2004年6月至2012年12月共330例受体进行心脏移植,均采用巴利昔单抗免疫诱导(术前2小时及术后第4天各20mg),按围术期肾功能情况分为血肌酐正常组(Cr<133μ mol/L;A组)、血肌酐升高组(Cr≥133μ mol/L;B组)、CRRT组(连续性肾替代治疗,C组),比较各组受体和供体术前资料、术后围术期恢复情况和死亡率,以及排异反应发生率.采用t检验、方差分析及卡方检验进行统计学比较分析.
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