In vitro and in vivo antiviral activities of matrix metalloproteinase 3 in a vesicular stomatitis vi

• 作 者: TINGTINGFENG;GUANGHAOLI;JIANFENGDAI;
• 机 构: 苏州大学
• 出 处: 中国免疫学会第十届全国免疫学学术大会
• 发表日期: 2015年期

　　Objectire: Vesicular stomatitis virus (Barber) is a single negative-stranded RNA virus that infects domestic and wild mammals.VSV is also commonly used as a virus model to study host anti-RNA virus responses.Using various in vitro infection models, we found that matrix metalloproteinase 3 (Eguchi et al.), also known as stromelysin-1, exhibited an antiviral activity against VSV infection.