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The responses of Sea Surface Temperature (SST) to greenhouse gas (GHG) and anthropogenic aerosol in the North Pacific are compared based on the historical and single-forcing simulations with Geophysical Fluid Dynamics Laboratory Climate Model version 3 (GFDL CM3).During 1860-2005, the GHG (aerosol) effect causes SST to warming (cooling) in the North Pacific, and they show some similarity and difference from each other.Specifically, it is found that this aerosol cooling effect exceeds the GHG warming effect in the Kuroshio/Oyashio Extension (KOE) region during 1950-2004 in the CM3 single forcing.It is simply because the responses to aerosol forcing consist of enhanced Aleutian Low, accelerated westerly of middle latitude and increased ocean sub-polar Gyre, which help increasing cold advection effect in the KOE region.Besides, the positive feedback effect between cold SST and cloud can also strengthen the aerosol cooling effect in the KOE region during the boreal summer, when the mixed layer depth is shallow.However, as response to GHG forcing, the increased subtropical Gyre and its warm advection effect are limited only in the Kuroshio Extension recirculation area and the maximum SST warming lies on the region north of 45°N during 1950-2004.Consequently, the SST responses to all forcing in the historical simulation are similar to the responses to aerosol forcing in sign and spatial pattern, and the aerosol effect is quite important to SST cooling in the mid-latitude North Pacific during the past 55 years.