Hepatitis C Virus-induced upregulation of miR-155 promotes hepatocarcinogenesis by activating Wnt si

来源 :2012遗传学进步促进粮食安全与人口健康高峰论坛 | 被引量 : 0次 | 上传用户:guofeng7303
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  Hepatitis C virus (HCV) infection usually induces chronic hepatic inflammation,which favors the initiation and progression of hepatocellular carcinoma.Moreover,microRNA-155 (miR-155) plays an important role in regulating both inflammation and tumorigenesis.However,little is known about whether and how miR-155 provides the link between inflammation and cancer.In this study,we found that miR-155 levels were markedly increased in patients infected with HCV.
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