类风湿关节炎中Th17-1ike Treg的表面分子标志鉴定及其免疫调节功能研究

来源 :中国免疫学会第九届全国免疫学学术大会 | 被引量 : 0次 | 上传用户：zj5536

【摘要】

：

研究背景:近年来的一系列研究发现,以表达IL-17A为标志的Th1 7-like Treg细胞可能参与自身免疫和炎症,是Treg研究的热点之一.然而,在人类自身免疫性疾病中,由于表面标志分子不明,该亚群难以实现活细胞分选及细胞功能评价,导致其在自身免疫疾病中的免疫调节功能特点还不能明确.目的:本研究致力于筛选Th1 7-like Treg的表面标志分子以实现该Treg亚群的活细胞分选,进而在此基础

【作者】

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孙晓麟李粼波王天朱雷朱华群张婧栗占国

【机构】

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北京大学人民医院首都医科大学附属北京安贞医院

【出处】

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中国免疫学会第九届全国免疫学学术大会

【发表日期】

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2014年8期

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类风湿关节炎中Th17-1ike Treg的表面分子标志鉴定及其免疫调节功能研究

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